The best time to use your baby bulb syringe is right after your baby gets out of the bath or shower. 
At this point everything in their precious little noses have softened up and is much easier to remove.
Another bonus of waiting until after bath time is that you have your little one wrapped in a towel. The towel will help keep their never moving hands down and away from their noses as you use the baby bulb syringe. The towel tip has been a big help around our house to make this part of the night run a lot smoother.
Buy the number one mucus removing tool used in hospitals; the hard to find blue hospital grade Baby Bulb Syringe.
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